SNP Report

Basic Info

Name	rs2709809 dbSNP Ensembl
Location	chr7:30602883 - 30602883(1)
Variant Alleles	C/A
Ancestral Allele	A
Minor Allele	C
Minor Allele Frequence	0.229633
Functional Annotation	intron_variant; NMD_transcript_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000389266, ENST00000454308, ENST00000478124, LRG_243t1); NMD_transcript_variant(ENST00000454308); non_coding_transcript_variant(ENST00000478124)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Ceulemans, S.,2011	C/A		Single SNP analyses: Permuted P-value = 0.1688, Odds Ratio=0...... Single SNP analyses: Permuted P-value = 0.1688, Odds Ratio=0.8237 More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
CRHR2	corticotropin releasing hormone receptor 2	7p14.3	3(2/1/0)
GARS	glycyl-tRNA synthetase	7p15	Mapped by Literature SNP

SNPs in LD with rs2709809 (count: 7) View in gBrowse (chr7:30574892..30657741 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs975537	intron_variant; NMD_transcript_variant	0.872[CEU]
rs38488	downstream_gene_variant; intron_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant	0.811[CEU]
rs1986756	intron_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[CEU]
rs2529437	intron_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[CEU]
rs38495	intron_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[CEU]
rs38494	intron_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant	1.0[CEU]
rs38487	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)