SNP Report

Basic Info

Name	rs2496353 dbSNP Ensembl
Location	chr6:118502372 - 118502372(1)
Variant Alleles	A/T
Ancestral Allele	T
Minor Allele	A
Minor Allele Frequence	0.0373403
Functional Annotation	intron_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000360290, ENST00000368488, ENST00000368491, ENST00000392500, ENST00000419517, ENST00000434604); non_coding_transcript_exon_variant(ENST00000469424); non_coding_transcript_variant(ENST00000469424)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Fan, J., 2010		A	P-value = 0.0099 in STEP2 sample; P-value = 0.0099 in STEP2 sample;	showed evidence of association in the replication sample showed evidence of association in the replication sample	Positive

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
CEP85L	centrosomal protein 85kDa-like	6q22.31	1(1/0/0)
BRD7P3	bromodomain containing 7 pseudogene 3	6q22.31	Mapped by Literature SNP

SNPs in LD with rs2496353 (count: 9) View in gBrowse (chr6:118367382..118635938 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs544160	intron_variant; non_coding_transcript_variant	0.866[CEU]
rs4946344		0.866[CEU]
rs2516262	intron_variant	0.866[CEU]
rs12662425		1.0[CEU]
rs579528	intron_variant; non_coding_transcript_variant	1.0[CEU]
rs10484285	intron_variant; non_coding_transcript_variant	1.0[CEU]
rs2496352	intron_variant; upstream_gene_variant	0.866[CEU]
rs7755056	intron_variant	1.0[CEU]
rs503031	intron_variant	1.0[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)