SNP Report

Basic Info

Name	rs2466046 dbSNP Ensembl
Location	chr8:32659643 - 32659643(1)
Variant Alleles	G/A
Ancestral Allele	G
Minor Allele	A
Minor Allele Frequence	0.417332
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000287842, ENST00000356819, ENST00000405005, ENST00000518104, ENST00000518206, ENST00000519301, ENST00000520407, ENST00000520502, ENST00000521670, ENST00000522569, ENST00000523041, ENST00000523079, ENST00000523534, ENST00000631040); non_coding_transcript_variant(ENST00000522569)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Cao L., 2014	A/G		Total BPI vs. controls: X²=1.96, OR=1.17, 95%CI=0...... Total BPI vs. controls: X²=1.96, OR=1.17, 95%CI=0.94-1.44, Bonf P-value=1; BPI-P vs. controls: X²=1.12, OR=1.14, 95%CI=0.90-1.45, Bonf P-value=1; BPI-NP vs. controls: X²=0.22, OR=1.09, 95%CI=0.77-1.53, Bonf P-value=1 More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
NRG1	neuregulin 1	8p12	15(10/5/0)

SNPs in LD with rs2466046 (count: 3) View in gBrowse (chr8:32659643..32680520 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs2976514	intron_variant; non_coding_transcript_variant	0.928[CHB]; 0.887[CHD]; 0.939[JPT]
rs2919392	intron_variant; non_coding_transcript_variant	1.0[CHB]; 1.0[JPT]
rs2466045	intron_variant; non_coding_transcript_variant	0.931[CHB]; 0.972[CHD]; 1.0[JPT]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)