SNP Report

Basic Info

Name	rs242937 dbSNP Ensembl
Location	chrCHR_HSCHR17_2_CTG5:45832621 - 45832621(1)
Variant Alleles	G/A
Ancestral Allele	A
Minor Allele	A
Minor Allele Frequence	0.357428
Functional Annotation	downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000587305); intron_variant(ENST00000293493, ENST00000314537, ENST00000339069, ENST00000347197, ENST00000352855, ENST00000398285, ENST00000577353, ENST00000580955, ENST00000582766, ENST00000583888, ENST00000619154, ENST00000634540, ENST00000634876); NMD_transcript_variant(ENST00000347197, ENST00000580955, ENST00000583888); non_coding_transcript_variant(ENST00000582766, ENST00000634876, ENST00000631500, ENST00000632599, ENST00000616225, ENST00000616274, ENST00000616748, ENST00000617905, ENST00000618144, ENST00000621969, ENST00000631395, ENST00000632383, ENST00000632552, ENST00000633723, ENST00000634181, ENST00000631395, ENST00000632383, ENST00000632552, ENST00000634181)
No. of Studies	2 (Positive: 0; Negative: 2; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Leszczynska-Rodziewicz, A., 2012	A/G		genotypic P-value = 0.08 genotypic P-value = 0.08	There were no significant differences for other polymorphism...... There were no significant differences for other polymorphisms in the studied group in comparison to the control group. More...	Negative
Leszczynska-Rodziewicz A, 2013	A/G		P-value=0.40 P-value=0.40	Neither genotypes nor alleles were significantly associated ...... Neither genotypes nor alleles were significantly associated with melancholic depression. More...	Negative

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
MAPT-AS1	MAPT antisense RNA 1	17q21.31	Mapped by Literature SNP
CRHR1	corticotropin releasing hormone receptor 1	17q21.31	4(2/2/0)

SNPs in LD with rs242937 (count: 0) View in gBrowse (chrCHR_HSCHR17_2_CTG5:45832621..45832621 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)