SNP Report

Basic Info

Name	rs2287921 dbSNP Ensembl
Location	chr19:48725015 - 48725015(1)
Variant Alleles	T/C
Ancestral Allele	T
Minor Allele	C
Minor Allele Frequence	0.216054
Functional Annotation	downstream_gene_variant; intron_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000594232); intron_variant(ENST00000222145, ENST00000599291); non_coding_transcript_exon_variant(ENST00000601530); non_coding_transcript_variant(ENST00000601530)
No. of Studies	2 (Positive: 0; Negative: 0; Trend: 2)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Green, E. K.,2012	C/T		BD ImmunoChip:P-value = 0.059,OR = 1.098;ImmunoChip, PGC-BD ...... BD ImmunoChip:P-value = 0.059,OR = 1.098;ImmunoChip, PGC-BD combined data:P-balue = 0.000000285,OR = 1.1 More...	Suggestive association was found. Suggestive association was found.	Trend
Sklar, P.,2011	C/T		Primary GWAS P-value(GC)=0.0000168, OR=1.12; replication P-v...... Primary GWAS P-value(GC)=0.0000168, OR=1.12; replication P-value(1-sided)=0.0137, OR=1.06; Combined GWAS and replication P-value(GC)=0.00000308, OR=1.1 More...	Suggestive association was found. Suggestive association was found.	Trend

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
RASIP1	Ras interacting protein 1	19q13.33	Mapped by Literature SNP

SNPs in LD with rs2287921 (count: 4) View in gBrowse (chr19:48725015..48746982 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs838147	downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant	0.851[CEU]
rs838144	downstream_gene_variant; upstream_gene_variant	0.851[CEU]
rs973579	downstream_gene_variant; intron_variant; upstream_gene_variant	0.851[CEU]
rs281408	intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.809[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)