BDgene

SNP Report

Basic Info
Name rs2217887 dbSNP Ensembl
Location chr14:79417482 - 79417482(1)
Variant Alleles T/C
Ancestral Allele C
Minor Allele C
Minor Allele Frequence 0.276158
Functional Annotation intron_variant; NMD_transcript_variant; non_coding_transcript_variant.
Consequence to Transcript intron_variant(ENST00000281127, ENST00000428277, ENST00000553803, ENST00000554719, ENST00000554738, ENST00000555073, ENST00000555387, ENST00000556003, ENST00000557594, ENST00000634499, ENST00000635466); NMD_transcript_variant(ENST00000554738, ENST00000555387); non_coding_transcript_variant(ENST00000553803, ENST00000555073, ENST00000556003)
No. of Studies 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Kuo, P. H., 2014 P-value=0.00233, OR=1.7, 95%CI=1.2-2.3 for the second stage...... P-value=0.00233, OR=1.7, 95%CI=1.2-2.3 for the second stage, combined P-value=0.02 for the replication stage. More... The marker is identified to be associated with bipolar disor...... The marker is identified to be associated with bipolar disorder in the fine-mapping stage with P-value less than 0.05. More... Positive

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
NRXN3 neurexin 3 14q31 2(2/0/0)

SNPs in LD with rs2217887 (count: 16) View in gBrowse (chr14:79381121..79421026 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 16)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)