BDgene

SNP Report

Basic Info
Name rs215006 dbSNP Ensembl
Location chr6:152434493 - 152434493(1)
Variant Alleles C/T
Ancestral Allele C
Minor Allele T
Minor Allele Frequence 0.302516
Functional Annotation 3_prime_UTR_variant; downstream_gene_variant; intron_variant; non_coding_transcript_variant.
Consequence to Transcript 3_prime_UTR_variant(ENST00000367248); downstream_gene_variant(ENST00000413186); intron_variant(ENST00000341594, ENST00000367253, ENST00000367255, ENST00000423061, ENST00000461872); non_coding_transcript_variant(ENST00000461872)
No. of Studies 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Xu, W., 2014 A/G P(unadj)-value=2.78E-04, OR (unadj)=1.335, P(adj)-value=7....... P(unadj)-value=2.78E-04, OR (unadj)=1.335, P(adj)-value=7.83E-05, OR (adj)=1.38 More... Top 68 SNPs (showing suggestive association to BD: p<0.0001)...... Top 68 SNPs (showing suggestive association to BD: p<0.0001) in our combined (CAMH and IoP) GWAS. SNPs from top 1000 from our combined CAMH/IoP GWAS for BPAD, for which at least one other non-overlapping GWAS also shows association at same gene. More... Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
SYNE1 spectrin repeat containing, nuclear envelope 1 6q25.2 6(3/2/1)

SNPs in LD with rs215006 (count: 9) View in gBrowse (chr6:152393994..152440860 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 9)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)