SNP Report

Basic Info

Name	rs2071084 dbSNP Ensembl
Location	chr14:96263805 - 96263805(1)
Variant Alleles	A/G
Ancestral Allele	G
Minor Allele	A
Minor Allele Frequence	0.165735
Functional Annotation	3_prime_UTR_variant; intron_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; synonymous_variant; upstream_gene_variant.
Consequence to Transcript	3_prime_UTR_variant(ENST00000553811); intron_variant(ENST00000553638); non_coding_transcript_exon_variant(ENST00000555847); non_coding_transcript_variant(ENST00000553638, ENST00000555847); synonymous_variant(ENST00000216629, ENST00000553356, ENST00000611804); upstream_gene_variant(ENST00000557122)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Gratacos, M.,2009			Single SNP association: In control and bipolar disorder samp...... Single SNP association: In control and bipolar disorder samples: Recessive Model, P-value = 0.0030(corrected by genomic control, Reus), P-value = 0.0012(passed multiple testing correction, Madrid); OR(95% CI): Reus: 4.71 (1.90-11.70), Madrid: 6.75 (1.88-24.22) More...	Nominal statistical significance was observed as P-value < 0...... Nominal statistical significance was observed as P-value < 0.05 using both control sets under the same genotypic mode. More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
BDKRB1	bradykinin receptor B1	14q32.1-q32.2	1(1/0/0)

SNPs in LD with rs2071084 (count: 5) View in gBrowse (chr14:96241120..96266654 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs875964	downstream_gene_variant; intron_variant; non_coding_transcript_variant	0.879[CEU]
rs2069600	downstream_gene_variant; intron_variant; non_coding_transcript_variant	0.812[CEU]
rs5224	intron_variant; synonymous_variant; upstream_gene_variant	0.869[CEU]
rs2069612	intron_variant; non_coding_transcript_variant	0.812[CEU]
rs2069588	3_prime_UTR_variant; downstream_gene_variant; intron_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant	0.812[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)