SNP Report

Basic Info

Name	rs1801133 dbSNP Ensembl
Location	chr1:11796321 - 11796321(1)
Variant Alleles	G/A
Ancestral Allele	G
Minor Allele	A
Minor Allele Frequence	0.245407
Functional Annotation	downstream_gene_variant; missense_variant. Polyphen Annotation: probably damaging(ENST00000376583, ENST00000376585, ENST00000376590, ENST00000376592, LRG_726t1) SIFT Annotation: deleterious(ENST00000376583, ENST00000376585, ENST00000376590, ENST00000376592, LRG_726t1)
Consequence to Transcript	downstream_gene_variant(ENST00000418034); missense_variant(ENST00000376583, ENST00000376585, ENST00000376590, ENST00000376592, LRG_726t1)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Yosifova, A.,2009	G/A		Allelic association: P-value = 0.15 Allelic association: P-value = 0.15	No significant association was observed No significant association was observed	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
MTHFR	methylenetetrahydrofolate reductase (NAD(P)H)	1p36.3	16(10/6/0)

SNPs in LD with rs1801133 (count: 0) View in gBrowse (chr1:11796321..11796321 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)