SNP Report

Basic Info

Name	rs17138171 dbSNP Ensembl
Location	chr11:79351885 - 79351885(1)
Variant Alleles	T/C
Ancestral Allele	T
Minor Allele	C
Minor Allele Frequence	0.108027
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000278550, ENST00000528688, ENST00000531583); non_coding_transcript_variant(ENST00000528688, ENST00000531583)
No. of Studies	2 (Positive: 1; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Chen, D. T.,2011		C	Meta-analysis results by ancestry: European-ancestry phase I...... Meta-analysis results by ancestry: European-ancestry phase I and phase II samples: Fixed effects P-value = 6.36E-07, Random effects P-value = 1.28E-07, I²=0, Q test=1.89, Q test P-value = 0.755 More...	No significant association was observed in BD. No significant association was observed in BD.	Negative
Muhleisen, T. W., 2014	C/T	C	MooDS: P-value=0.0261, OR=1.14; PGC: P-value=1.06E-7, OR=1.1...... MooDS: P-value=0.0261, OR=1.14; PGC: P-value=1.06E-7, OR=1.18; MooDS-PGC: P-value=1.02E-8, adjusted P-value=1.37E-8, OR=1.16 More...	Eighteen GWAS SNPs showing genome-wide evidence for associat...... Eighteen GWAS SNPs showing genome-wide evidence for association with BD in the combined MooDS and PGC samples. More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
TENM4	teneurin transmembrane protein 4	11q13	6(4/2/0)

SNPs in LD with rs17138171 (count: 5) View in gBrowse (chr11:79346052..79367625 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs11237805	intron_variant; non_coding_transcript_variant	0.93[CEU]
rs954129	intron_variant; non_coding_transcript_variant	0.936[CEU]; 0.911[TSI]
rs11237796	intron_variant; non_coding_transcript_variant	0.936[CEU]; 0.911[TSI]
rs12279388	intron_variant; non_coding_transcript_variant	1.0[CEU]
rs12577093	intron_variant; non_coding_transcript_variant	0.936[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)