SNP Report

Basic Info

Name	rs16879552 dbSNP Ensembl
Location	chr8:32553698 - 32553698(1)
Variant Alleles	C/T
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.214457
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000287842, ENST00000356819, ENST00000405005, ENST00000518104, ENST00000519301, ENST00000520407, ENST00000521670, ENST00000523079, ENST00000523534, ENST00000631040)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Cao L., 2014	G/A		Total BPI vs. controls: X²=1.46, OR=1.13, 95%CI=0...... Total BPI vs. controls: X²=1.46, OR=1.13, 95%CI=0.93-1.36, Bonf P-value=1; BPI-P vs. controls: X²=0.28, OR=1.06, 95%CI=0.85-1.32, Bonf P-value=1; BPI-NP vs. controls: X²=2.19, OR=1.26, 95%CI=0.93-1.72, Bonf P-value=1 More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
NRG1	neuregulin 1	8p12	15(10/5/0)

SNPs in LD with rs16879552 (count: 9) View in gBrowse (chr8:32526430..32558300 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs10088313	intron_variant	0.893[CHB]; 0.822[JPT]
rs4624987	intron_variant	0.899[CHB]; 0.85[JPT]
rs3884552	intron_variant	0.828[JPT]
rs10094655	intron_variant	0.899[CHB]; 1.0[CHD]
rs10113593	intron_variant	0.854[CHB]
rs10107065	intron_variant	0.854[CHB]; 0.838[CHD]; 0.85[JPT]
rs16879557	intron_variant	0.804[CHD]; 0.9[JPT]
rs10113578	intron_variant	0.854[CHB]
rs7830563	intron_variant	0.854[CHB]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)