SNP Report

Basic Info

Name	rs1551683 dbSNP Ensembl
Location	chr10:60390601 - 60390601(1)
Variant Alleles	C/T
Ancestral Allele	T
Minor Allele	T
Minor Allele Frequence	0.0896565
Functional Annotation	intron_variant; NMD_transcript_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000373827, ENST00000503366, ENST00000622427); NMD_transcript_variant(ENST00000622427); upstream_gene_variant(ENST00000280772)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Fiorentino A., 2014	C/T		eurMLP=0.48 eurMLP=0.48	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
ANK3	ankyrin 3, node of Ranvier (ankyrin G)	10q21	17(13/3/1)

SNPs in LD with rs1551683 (count: 5) View in gBrowse (chr10:60384036..60410869 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs7100330	intron_variant; NMD_transcript_variant	1.0[CEU]
rs7099869	intron_variant; NMD_transcript_variant	0.923[CEU]; 0.944[TSI]
rs7896287	intron_variant; NMD_transcript_variant	1.0[CEU]; 1.0[TSI]
rs7907761	intron_variant; NMD_transcript_variant	1.0[CEU]
rs7082025	intron_variant; NMD_transcript_variant; upstream_gene_variant	1.0[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)