SNP Report

Basic Info

Name	rs148468662 dbSNP Ensembl
Location	chr8:20179196 - 20179196(1)
Variant Alleles	C/A/T
Ancestral Allele	C
Minor Allele	A
Minor Allele Frequence	1.99681E-4
Functional Annotation	missense_variant; NMD_transcript_variant; upstream_gene_variant. Polyphen Annotation: possibly damaging(ENST00000265808, ENST00000276373, ENST00000440926, ENST00000519026); benign(ENST00000381608, ENST00000437980, ENST00000517776, ENST00000522513) SIFT Annotation: tolerated(ENST00000381608, ENST00000437980, ENST00000517776, ENST00000522513, ENST00000265808, ENST00000276373, ENST00000440926, ENST00000519026)
Consequence to Transcript	missense_variant(ENST00000381608, ENST00000437980, ENST00000517776, ENST00000522513, ENST00000265808, ENST00000276373, ENST00000440926, ENST00000519026); NMD_transcript_variant(ENST00000517776); upstream_gene_variant(ENST00000524272)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Lohoff, F. W., 2013			P-value=0.199 P-value=0.199	DNA Sanger sequencing of BPD patients identified several nov...... DNA Sanger sequencing of BPD patients identified several novel and rare variants. The Leu138 frequency did not differ statistically between cases and controls. More...	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
SLC18A1	solute carrier family 18 (vesicular monoamine transporter), member 1	8p21.3	3(2/1/0)

SNPs in LD with rs148468662 (count: 0) View in gBrowse (chr8:20179196..20179196 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)