SNP Report

Basic Info

Name	rs147527383 dbSNP Ensembl
Location	chr10:60070193 - 60070193(1)
Variant Alleles	T/C
Ancestral Allele	T
Minor Allele	C
Minor Allele Frequence	0.00119808
Functional Annotation	intron_variant; missense_variant; NMD_transcript_variant. Polyphen Annotation: benign(ENST00000621739, ENST00000280772); possibly damaging(ENST00000610901, ENST00000613207) SIFT Annotation: deleterious(ENST00000621739); deleterious - low confidence(ENST00000280772, ENST00000610901, ENST00000613207)
Consequence to Transcript	intron_variant(ENST00000355288, ENST00000373820, ENST00000373827, ENST00000503366, ENST00000511043, ENST00000610321, ENST00000616444); missense_variant(ENST00000621739, ENST00000280772, ENST00000610901, ENST00000613207); NMD_transcript_variant(ENST00000621739)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Fiorentino A., 2014	T/C		eurMLP=0.31 eurMLP=0.31	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
ANK3	ankyrin 3, node of Ranvier (ankyrin G)	10q21	17(13/3/1)

SNPs in LD with rs147527383 (count: 0) View in gBrowse (chr10:60070193..60070193 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)