SNP Report

Basic Info

Name	rs1459005 dbSNP Ensembl
Location	chr8:112902910 - 112902910(1)
Variant Alleles	T/C
Ancestral Allele	T
Minor Allele	C
Minor Allele Frequence	0.023762
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000297405, ENST00000343508, ENST00000455883)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Xu, W., 2014	G/A		P-value=9.45E-05 P-value=9.45E-05	Top 132 SNPs (showing suggestive association to BD in our CA...... Top 132 SNPs (showing suggestive association to BD in our CAMH family cohort: p<0.0001). More...	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
CSMD3	CUB and Sushi multiple domains 3	8q23.3	1(0/1/0)

SNPs in LD with rs1459005 (count: 9) View in gBrowse (chr8:112849858..112902910 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs231299	intron_variant	1.0[CEU]; 1.0[TSI]
rs231307	intron_variant	1.0[CEU]; 1.0[TSI]
rs231326	intron_variant	1.0[CEU]; 1.0[TSI]
rs231303	intron_variant	1.0[CEU]; 1.0[TSI]
rs231311	intron_variant	1.0[CEU]; 1.0[TSI]
rs231327	intron_variant	1.0[CEU]
rs6982356	intron_variant	1.0[CEU]
rs231325	intron_variant	1.0[CEU]
rs10505195	intron_variant	1.0[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)