BDgene

SNP Report

Basic Info
Name rs12494223 dbSNP Ensembl
Location chr3:21580304 - 21580304(1)
Variant Alleles C/T
Ancestral Allele T
Minor Allele T
Minor Allele Frequence 0.111821
Functional Annotation downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant.
Consequence to Transcript downstream_gene_variant(ENST00000412369); intron_variant(ENST00000281523, ENST00000446749, ENST00000478967, ENST00000494108, ENST00000494118); NMD_transcript_variant(ENST00000446749); non_coding_transcript_variant(ENST00000478967, ENST00000494108, ENST00000494118)
No. of Studies 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Xu, W., 2014 T/C Adjusted P (ADD)=1.44E-04， OR=0.7548 Adjusted P (ADD)=1.44E-04， OR=0.7548 SNPs from top 1000 from our combined CAMH/IoP GWAS for BPAD,...... SNPs from top 1000 from our combined CAMH/IoP GWAS for BPAD, for which at least one other non-overlapping GWAS also shows association at same gene. More... Negative

SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
ZNF385D zinc finger protein 385D 3p24.3 1(0/1/0)
ZNF385D-AS1 ZNF385D antisense RNA 1 3p24.3 Mapped by Literature SNP

SNPs in LD with rs12494223 (count: 5) View in gBrowse (chr3:21553365..21595141 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 5)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback Acknowledgements
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Last update: March 31, 2016