SNP Report

Basic Info

Name	rs12485389 dbSNP Ensembl
Location	chr3:16876050 - 16876050(1)
Variant Alleles	A/G
Ancestral Allele	A
Minor Allele	G
Minor Allele Frequence	0.0880591
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000460467); non_coding_transcript_variant(ENST00000460467)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Xu, W., 2014	G/A		P(unadj)-value=7.11E-04,Â OR (unadj)=1.508,Â P(adj)-value=8....... P(unadj)-value=7.11E-04,Â OR (unadj)=1.508,Â P(adj)-value=8.20E-05,Â OR (adj)=1.64 More...	Top 68 SNPs (showing suggestive association to BD: p<0.0001)...... Top 68 SNPs (showing suggestive association to BD: p<0.0001) in our combined (CAMH and IoP) GWAS. More...	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
PLCL2	phospholipase C-like 2	3p24.3	1(0/1/0)

SNPs in LD with rs12485389 (count: 2) View in gBrowse (chr3:16843728..16876050 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs6796746		intron_variant; non_coding_transcript_variant	0.884[TSI]
rs12497413		intron_variant; non_coding_transcript_variant	0.884[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)