SNP Report

Basic Info

Name	rs12153828 dbSNP Ensembl
Location	chr6:118659949 - 118659949(1)
Variant Alleles	G/C
Ancestral Allele	G
Minor Allele	C
Minor Allele Frequence	0.0946486
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000368488, ENST00000392500, ENST00000434604, ENST00000489276); non_coding_transcript_variant(ENST00000489276)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Fan, J., 2010		G	P-value = 0.039 in STEP2 sample; P-value = 0.039 in STEP2 sample;	showed evidence of association in the replication sample showed evidence of association in the replication sample	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
CEP85L	centrosomal protein 85kDa-like	6q22.31	1(1/0/0)

SNPs in LD with rs12153828 (count: 6) View in gBrowse (chr6:118507780..118665065 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs9320664	intron_variant; upstream_gene_variant	0.849[CEU]
rs12210025	intron_variant; non_coding_transcript_variant	1.0[CEU]
rs12189855	downstream_gene_variant; intron_variant; upstream_gene_variant	1.0[CEU]
rs12153955	intron_variant	0.866[CEU]
rs12203311	downstream_gene_variant; intron_variant	0.866[CEU]
rs6941759	downstream_gene_variant; intron_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant	0.866[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)