SNP Report

Basic Info

Name	rs1176744 dbSNP Ensembl
Location	chr11:113932306 - 113932306(1)
Variant Alleles	A/C
Ancestral Allele	C
Minor Allele	C
Minor Allele Frequence	0.354433
Functional Annotation	missense_variant. Polyphen Annotation: benign(ENST00000260191, ENST00000537778, ENST00000543092) SIFT Annotation: tolerated(ENST00000260191, ENST00000537778, ENST00000543092)
Consequence to Transcript	missense_variant(ENST00000260191, ENST00000537778, ENST00000543092)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Yosifova, A.,2009	A/C		Allelic association: P-value = 0.5 Allelic association: P-value = 0.5	No significant association was observed No significant association was observed	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
HTR3B	5-hydroxytryptamine (serotonin) receptor 3B, ionotropic	11q23.1	2(1/1/0)

SNPs in LD with rs1176744 (count: 5) View in gBrowse (chr11:113904553..113933386 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs1176743	intron_variant	0.906[CEU]; 1.0[TSI]
rs7103572	intron_variant	0.901[CEU]
rs4938058	intron_variant	0.901[CEU]; 0.837[TSI]
rs3758987	upstream_gene_variant	0.841[CEU]
rs11214769	intron_variant	0.901[CEU]; 0.837[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)