BDgene

SNP Report

Basic Info
Name rs11684394 dbSNP Ensembl
Location chr2:75216947 - 75216947(1)
Variant Alleles C/T
Ancestral Allele C
Minor Allele T
Minor Allele Frequence 0.203674
No. of Studies 2 (Positive: 2; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 2)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Sharp S.I., 2014 C/T P-value=0.006, OR=0.52, 95%CI=0.32-0.84 P-value=0.006, OR=0.52, 95%CI=0.32-0.84 Significant association was observed. Significant association was observed. Positive
Gratacos, M.,2009 Single SNP association: In control and bipolar disorder samp...... Single SNP association: In control and bipolar disorder samples: Dominant Model, P-value = 0.0063(corrected by genomic control, Reus), P-value = 0.0005(passed multiple testing correction, Madrid); OR(95% CI): Reus: 0.61 (0.44-0.85), Madrid: 20.440.53 (0.36-0.76) More... Nominal statistical significance was observed as P-value < 0...... Nominal statistical significance was observed as P-value < 0.05 using both control sets under the same genotypic mode. More... Positive

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
TACR1 tachykinin receptor 1 2p13.1-p12 3(3/0/0)

SNPs in LD with rs11684394 (count: 1) View in gBrowse (chr2:75216947..75224602 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 1)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)