BDgene

SNP Report

Basic Info
Name rs11196201 dbSNP Ensembl
Location chr10:113043548 - 113043548(1)
Variant Alleles A/T
Ancestral Allele A
Minor Allele T
Minor Allele Frequence 0.0471246
Functional Annotation intron_variant.
Consequence to Transcript intron_variant(ENST00000346198, ENST00000352065, ENST00000355717, ENST00000355995, ENST00000369395, ENST00000369397, ENST00000534894, ENST00000536810, ENST00000538897, ENST00000542695, ENST00000543371, ENST00000545257, ENST00000627217, ENST00000629706)
No. of Studies 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Cuellar-Barboza, A. B., 2016 T SNP main effect: P-value=0.15, OR=0.82; SNP-BMI interaction...... SNP main effect: P-value=0.15, OR=0.82; SNP-BMI interaction: P-value=0.71, OR=0.99 More... Consistent with the discovery study, the SNPs showed no marg...... Consistent with the discovery study, the SNPs showed no marginal effect on BD risk, either unadjusted or adjusted for BMI (all p > 0.05); however, seven out of the 26 genotyped TCF7L2 SNPs showed a significant SNP–BMI interaction effect, with p < 0.05. More... Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 10q25.3 1(1/0/0)

SNPs in LD with rs11196201 (count: 3) View in gBrowse (chr10:112999686..113043548 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 3)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)