BDgene

SNP Report

Basic Info
Name rs11030104 dbSNP Ensembl
Location chr11:27662970 - 27662970(1)
Variant Alleles A/G
Ancestral Allele A
Minor Allele G
Minor Allele Frequence 0.222644
Functional Annotation downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript downstream_gene_variant(ENST00000530313, ENST00000532965); intron_variant(ENST00000314915, ENST00000356660, ENST00000395978, ENST00000395980, ENST00000395981, ENST00000395983, ENST00000395986, ENST00000418212, ENST00000420794, ENST00000438929, ENST00000499008, ENST00000499568, ENST00000500662, ENST00000501176, ENST00000502161, ENST00000525950, ENST00000530686, ENST00000530786, ENST00000530861, ENST00000532997, ENST00000533131, ENST00000533246, ENST00000584049); NMD_transcript_variant(ENST00000530786); non_coding_transcript_variant(ENST00000499008, ENST00000499568, ENST00000500662, ENST00000501176, ENST00000502161, ENST00000530686, ENST00000584049); upstream_gene_variant(ENST00000439476, ENST00000501663, ENST00000525528)
No. of Studies 2 (Positive: 1; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 2)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Sears, C.,2011 C FBAT: MAF=0.206, P-value = 0.004 FBAT: MAF=0.206, P-value = 0.004 Significant association was found . Significant association was found . Positive
Liu, L., 2008 Average PDT statistic P-value = 0.78 for the model 1; avera...... Average PDT statistic P-value = 0.78 for the model 1; average PDT statistic P-value = 0.87 for the model 2; average PDT statistic P-value = 0.35 for the model 3 between the SNP and bipolar disorder. More... This SNP did not provide evidence of association using any o...... This SNP did not provide evidence of association using any of the three disease models. More... Negative

SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
BDNF brain-derived neurotrophic factor 11p14.1 37(24/12/1)
BDNF-AS BDNF antisense RNA 11p14.1 Mapped by Literature SNP

SNPs in LD with rs11030104 (count: 29) View in gBrowse (chr11:27520076..27706992 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 29)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback Acknowledgements
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Last update: March 31, 2016