SNP Report

Basic Info

Name	rs11013860 dbSNP Ensembl
Location	chr10:18365098 - 18365098(1)
Variant Alleles	A/C
Ancestral Allele	A
Minor Allele	C
Minor Allele Frequence	0.210663
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000282343, ENST00000324631, ENST00000352115, ENST00000377319, ENST00000377328, ENST00000377329, ENST00000377331, ENST00000396576, ENST00000498816, ENST00000612134, ENST00000612743, ENST00000615785, ENST00000617363); non_coding_transcript_variant(ENST00000498816)
No. of Studies	2 (Positive: 1; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Jan, W. C., 2014	C/A		OR=1.36, 95%CI=1.02-1.81, P-value=0.04 for BD-I; OR=1.3, 95%...... OR=1.36, 95%CI=1.02-1.81, P-value=0.04 for BD-I; OR=1.3, 95%CI=0.75-2.25, P-value=0.36 for BD-II. P-value = 1.04E-06 for the combined analysis. More...	For the Î² subunit, marker rs11013860 in CACNB2 genewas asso...... For the Î² subunit, marker rs11013860 in CACNB2 genewas associated with BP-I (OR=1.36, P=0.04, empirical P=0.038). More...	Positive
Lee, M. T.,2011	A/C		Genome-wide association: in joint analysis, CC vs. AA+AC, P-...... Genome-wide association: in joint analysis, CC vs. AA+AC, P-value = 5.15E-05; genotype , P-value = 5.54E-04 More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
CACNB2	calcium channel, voltage-dependent, beta 2 subunit	10p12	3(2/1/0)

SNPs in LD with rs11013860 (count: 1) View in gBrowse (chr10:18364263..18365098 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs7907743		intron_variant; non_coding_transcript_variant	0.813[CHB]; 0.863[JPT]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)