SNP Report

Basic Info

Name	rs10994338 dbSNP Ensembl
Location	chr10:60421370 - 60421370(1)
Variant Alleles	G/A
Ancestral Allele	G
Minor Allele	A
Minor Allele Frequence	0.123403
Functional Annotation	intron_variant; NMD_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000373827, ENST00000503366, ENST00000622427); NMD_transcript_variant(ENST00000622427)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	YES

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Liu, Y.,2011			Meta analysis: P-value = 9.1E-09 Meta analysis: P-value = 9.1E-09	Significant association was found . Significant association was found .	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
ANK3	ankyrin 3, node of Ranvier (ankyrin G)	10q21	17(13/3/1)

SNPs in LD with rs10994338 (count: 0) View in gBrowse (chr10:60421370..60421370 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Liu, Y.,2011	Meta analysis:P-value = 4.8E-07	Suggestive association was found.	Trend