SNP Report

Basic Info

Name	rs10994285 dbSNP Ensembl
Location	chr10:60255249 - 60255249(1)
Variant Alleles	C/T
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.167931
Functional Annotation	intron_variant; NMD_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000280772, ENST00000373827, ENST00000503366, ENST00000503925, ENST00000622427); NMD_transcript_variant(ENST00000622427)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Dedman, A.,2012	T/C		Association analysis: for UCL1 sample, P-value = 0.041, OR=1...... Association analysis: for UCL1 sample, P-value = 0.041, OR=1.58; for UCL2 sample, P-value = 0.91, OR=0.976; for UCL1+UCL2 sample, P-value = 0.11, OR=1.28 More...	Significant association was observed in BD. Significant association was observed in BD.	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
ANK3	ankyrin 3, node of Ranvier (ankyrin G)	10q21	17(13/3/1)

SNPs in LD with rs10994285 (count: 1) View in gBrowse (chr10:60255249..60285940 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs10994293		intron_variant; NMD_transcript_variant	0.858[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)