SNP Report

Basic Info

Name	rs10954862 dbSNP Ensembl
Location	chr8:32588592 - 32588592(1)
Variant Alleles	G/A
Ancestral Allele	G
Minor Allele	A
Minor Allele Frequence	0.278554
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000287842, ENST00000356819, ENST00000405005, ENST00000518104, ENST00000519301, ENST00000520407, ENST00000521670, ENST00000523079, ENST00000523534, ENST00000631040)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Cao L., 2014	A/G		Total BPI vs. controls: X²=0.58, OR=0.91, 95%CI=0...... Total BPI vs. controls: X²=0.58, OR=0.91, 95%CI=0.64-1.30, Bonf P-value=1; BPI-P vs. controls: X²=0.56, OR=0.9, 95%CI=0.67-1.19, Bonf P-value=1; BPI-NP vs. controls: X²=0.13, OR=0.93, 95%CI=0.61-1.39, Bonf P-value=1 More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
NRG1	neuregulin 1	8p12	15(10/5/0)

SNPs in LD with rs10954862 (count: 20) View in gBrowse (chr8:32580411..32591213 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs10954859	intron_variant	1.0[CHB]; 0.914[JPT]
rs17665212	intron_variant	1.0[CHB]; 1.0[JPT]
rs10954858	intron_variant	1.0[CHB]; 0.93[JPT]
rs10954857	intron_variant	1.0[CHB]; 0.93[JPT]
rs7826436	intron_variant	1.0[CHB]; 0.93[JPT]
rs2466094	intron_variant	1.0[CHB]; 1.0[JPT]
rs17721098	intron_variant	1.0[CHB]; 0.923[JPT]
rs2466062	intron_variant	1.0[CHB]; 0.923[JPT]
rs4298457	intron_variant	1.0[CHB]; 0.923[JPT]
rs4302803	intron_variant	1.0[CHB]; 0.929[JPT]
rs2439291	intron_variant	1.0[CHB]; 1.0[JPT]
rs10503921	intron_variant	0.834[CHB]; 0.926[JPT]
rs17721282	intron_variant	1.0[CHB]; 0.929[JPT]
rs4272338	intron_variant	1.0[CHB]; 0.918[JPT]
rs10954860	intron_variant	1.0[CHB]; 0.918[JPT]
rs7826814	intron_variant	1.0[CHB]; 0.93[JPT]
rs4521724	intron_variant	0.911[CHB]; 0.925[JPT]
rs6999843	intron_variant	1.0[CHB]; 0.93[JPT]
rs17721372	intron_variant	1.0[CHB]; 0.923[JPT]
rs2439290	intron_variant	1.0[CHB]; 1.0[JPT]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)