SNP Report

Basic Info

Name	rs10821745 dbSNP Ensembl
Location	chr10:60376448 - 60376448(1)
Variant Alleles	T/G
Ancestral Allele	T
Minor Allele	G
Minor Allele Frequence	0.150759
Functional Annotation	intron_variant; NMD_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000280772, ENST00000373827, ENST00000503366, ENST00000622427); NMD_transcript_variant(ENST00000622427)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Muhleisen, T. W., 2014	G/T	G	MooDS: P-value=0.1691, OR=1.08; PGC: P-value=2.33E-9, OR=1.3...... MooDS: P-value=0.1691, OR=1.08; PGC: P-value=2.33E-9, OR=1.35; MooDS-PGC: P-value=9.41E-9, adjusted P-value=1.26E-8, OR=1.27 More...	Eighteen GWAS SNPs showing genome-wide evidence for associat...... Eighteen GWAS SNPs showing genome-wide evidence for association with BD in the combined MooDS and PGC samples. More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
ANK3	ankyrin 3, node of Ranvier (ankyrin G)	10q21	17(13/3/1)

SNPs in LD with rs10821745 (count: 6) View in gBrowse (chr10:60337573..60403569 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs4948412	intron_variant; NMD_transcript_variant	1.0[CEU]; 1.0[TSI]
rs1380459	intron_variant; NMD_transcript_variant	1.0[CEU]; 0.911[TSI]
rs12416380	intron_variant; NMD_transcript_variant	1.0[CEU]
rs10994329	intron_variant; NMD_transcript_variant	1.0[CEU]; 1.0[TSI]
rs4948417	intron_variant; NMD_transcript_variant	1.0[CEU]; 1.0[TSI]
rs10994322	intron_variant; NMD_transcript_variant	1.0[CEU]; 0.911[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)