SNP Report

Basic Info

Name	rs10509129 dbSNP Ensembl
Location	chr10:60311283 - 60311283(1)
Variant Alleles	G/A/T
Ancestral Allele	G
Minor Allele	T
Minor Allele Frequence	0.0930511
Functional Annotation	intron_variant; NMD_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000280772, ENST00000373827, ENST00000503366, ENST00000622427); NMD_transcript_variant(ENST00000622427)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Muhleisen, T. W., 2014	T/G	T	MooDS: P-value=0.34, OR=1.09; PGC: P-value=5.57E-9, OR=1.36;...... MooDS: P-value=0.34, OR=1.09; PGC: P-value=5.57E-9, OR=1.36; MooDS-PGC: P-value=3.64E-8, adjusted P-value=4.77E-8, OR=1.29 More...	Eighteen GWAS SNPs showing genome-wide evidence for associat...... Eighteen GWAS SNPs showing genome-wide evidence for association with BD in the combined MooDS and PGC samples. More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
ANK3	ankyrin 3, node of Ranvier (ankyrin G)	10q21	17(13/3/1)

SNPs in LD with rs10509129 (count: 1) View in gBrowse (chr10:60300624..60311283 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs10761473		intron_variant; NMD_transcript_variant; upstream_gene_variant	1.0[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)