SNP Report

Basic Info

Name	rs10278591 dbSNP Ensembl
Location	chr7:1881726 - 1881726(1)
Variant Alleles	C/T
Ancestral Allele	T
Minor Allele	T
Minor Allele Frequence	0.351038
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000265854, ENST00000399654, ENST00000402746, ENST00000406869, ENST00000450235)
No. of Studies	1 (Positive: 0; Negative: 0; Trend: 1)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Cichon, S.,2011		T	For GWAS, P-value = 0.00000605, OR=1.43, for Replication I, ...... For GWAS, P-value = 0.00000605, OR=1.43, for Replication I, P-value = 0.0348, OR=1.12, for combined sample(GWAS+Replication I), P-value = 0.0000181, OR=1.21 More...	Suggestive association was found. Suggestive association was found.	Trend

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
MAD1L1	MAD1 mitotic arrest deficient-like 1 (yeast)	7p22	5(1/2/2)

SNPs in LD with rs10278591 (count: 7) View in gBrowse (chr7:1852087..1924721 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs10268609	intron_variant	0.849[CEU]
rs11770148	intron_variant; non_coding_transcript_variant	0.849[CEU]
rs7788921	intron_variant; upstream_gene_variant	0.927[CEU]; 1.0[TSI]
rs11764337	downstream_gene_variant; intron_variant; non_coding_transcript_variant	0.805[CEU]
rs11764124	downstream_gene_variant; intron_variant; non_coding_transcript_variant	0.845[CEU]
rs4719331	intron_variant; upstream_gene_variant	0.927[CEU]; 1.0[TSI]
rs1403175	intron_variant	0.849[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)