BDgene

Region Report

Basic Info
Region Name 4q31
Chromosome Position chr4:138500000-154600000
No. of Studies (Positive/Negative/Trend)  5(1/0/4)

Region related studies (count: 5)
Reference Markers Statistical Values Author Comments Result Category
Xu, H.,2011 D4S1625 Linkage study: for BP3, Dominant model, LOD = 0.25 for New p...... Linkage study: for BP3, Dominant model, LOD = 0.25 for New pedigrees(N = 16), LOD = 1.94 for all pedigrees(N = 56); More... Suggestive linkage was found in this region. Suggestive linkage was found in this region. Trend
Xu, H.,2010 D4S1625 linkage study: for BP3, Dominant model, LOD = 0.25 in new pe...... linkage study: for BP3, Dominant model, LOD = 0.25 in new pedigrees(N = 16); LOD = 1.94 in all pedigrees(N = 56) More... Suggestive linkage was found in this region. Suggestive linkage was found in this region. Trend
Schumacher, J.,2005 Linkage Analysis: for Fine-mapping sample, ASDI(only includi...... Linkage Analysis: for Fine-mapping sample, ASDI(only including BPI) NPL = 2.85, P-value = 0.01; ASDII(including BPI, BPII, or SA/BP) NPL = 3.18, P-value = 0.004; ASDIII(including BPI, BPII, SA/BP, or UPR) NPL = 2.36, P-value = 0.016; for Romany subsample, ASDI(only including BPI) NPL = 3.52, P-value = 0.014; ASDII(including BPI, BPII, or SA/BP) NPL = 3.34, P-value = 0.016; ASDIII(including BPI, BPII, SA/BP, or UPR) NPL = 5.49, P-value = 0.015; for German subsample, ASDI(only including BPI) NPL = 2.15, P-value = 0.038; ASDII(including BPI, BPII, or SA/BP) NPL = 2.58, P-value = 0.012; ASDIII(including BPI, BPII, SA/BP, or UPR) NPL = 1.61, P-value = 0.244; for Bulgarian subsample, ASDI(only including BPI) NPL = 1.29, P-value = 0.258; ASDII(including BPI, BPII, or SA/BP) NPL = 1.28, P-value = 0.244 More... Significant linkage was found in this region. Significant linkage was found in this region. Positive
Kaneva, R.,2009 D4S420, D4S1644, D4S424, D4S2981, D4S1604, D4S1586, D4S3014, D4S1606, D4S1548, D4S2934, D4S2976, D4S1625, D4S2962, D4S1588, D4S2999 Linkage analysis: For marker D4S1625, recessive model, two-p...... Linkage analysis: For marker D4S1625, recessive model, two-point LOD = 2.78, P-value = 0.000172; For marker D4S2962, recessive model, two-point LOD = 2.59, P-value = 0.000276; For marker D4S1588, recessive model, two-point LOD = 2.24, P-value = 0.000665; For marker D4S2999, recessive model, two-point LOD = 3.18, P-value = 0.000065 More... There is a trend for Significant linkage. There is a trend for Significant linkage. Trend
Liu, J.,2003 D4S1625 Two-point parametric linkage results: Maximum LOD = 3.16, Mo...... Two-point parametric linkage results: Maximum LOD = 3.16, Model BP3, Dominant, theta = 0.15 More... Suggestive linkage was found in this region. Suggestive linkage was found in this region. Trend

Region related genes (count: 2)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 4q13 1(0/0/1)
NR3C2 nuclear receptor subfamily 3, group C, member 2 4q31 1(1/0/0)

View in gBrowse

Region: chr4:138500000..154600000 View in gBrowse
View in gBrowse