BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

Search Gene with Disease Search Gene1 with Disease

Region Report

Basic Info

Region Name	4q31
Chromosome Position	chr4:138500000-154600000
No. of Studies (Positive/Negative/Trend)	5(1/0/4)

Region related studies (count: 5)

Reference	Markers	Statistical Values	Author Comments	Result Category
Xu, H.,2011	D4S1625	Linkage study: for BP3, Dominant model, LOD = 0.25 for New p...... Linkage study: for BP3, Dominant model, LOD = 0.25 for New pedigrees(N = 16), LOD = 1.94 for all pedigrees(N = 56); More...	Suggestive linkage was found in this region. Suggestive linkage was found in this region.	Trend
Xu, H.,2010	D4S1625	linkage study: for BP3, Dominant model, LOD = 0.25 in new pe...... linkage study: for BP3, Dominant model, LOD = 0.25 in new pedigrees(N = 16); LOD = 1.94 in all pedigrees(N = 56) More...	Suggestive linkage was found in this region. Suggestive linkage was found in this region.	Trend
Schumacher, J.,2005		Linkage Analysis: for Fine-mapping sample, ASDI(only includi...... Linkage Analysis: for Fine-mapping sample, ASDI(only including BPI) NPL = 2.85, P-value = 0.01; ASDII(including BPI, BPII, or SA/BP) NPL = 3.18, P-value = 0.004; ASDIII(including BPI, BPII, SA/BP, or UPR) NPL = 2.36, P-value = 0.016; for Romany subsample, ASDI(only including BPI) NPL = 3.52, P-value = 0.014; ASDII(including BPI, BPII, or SA/BP) NPL = 3.34, P-value = 0.016; ASDIII(including BPI, BPII, SA/BP, or UPR) NPL = 5.49, P-value = 0.015; for German subsample, ASDI(only including BPI) NPL = 2.15, P-value = 0.038; ASDII(including BPI, BPII, or SA/BP) NPL = 2.58, P-value = 0.012; ASDIII(including BPI, BPII, SA/BP, or UPR) NPL = 1.61, P-value = 0.244; for Bulgarian subsample, ASDI(only including BPI) NPL = 1.29, P-value = 0.258; ASDII(including BPI, BPII, or SA/BP) NPL = 1.28, P-value = 0.244 More...	Significant linkage was found in this region. Significant linkage was found in this region.	Positive
Kaneva, R.,2009	D4S420, D4S1644, D4S424, D4S2981, D4S1604, D4S1586, D4S3014, D4S1606, D4S1548, D4S2934, D4S2976, D4S1625, D4S2962, D4S1588, D4S2999	Linkage analysis: For marker D4S1625, recessive model, two-p...... Linkage analysis: For marker D4S1625, recessive model, two-point LOD = 2.78, P-value = 0.000172; For marker D4S2962, recessive model, two-point LOD = 2.59, P-value = 0.000276; For marker D4S1588, recessive model, two-point LOD = 2.24, P-value = 0.000665; For marker D4S2999, recessive model, two-point LOD = 3.18, P-value = 0.000065 More...	There is a trend for Significant linkage. There is a trend for Significant linkage.	Trend
Liu, J.,2003	D4S1625	Two-point parametric linkage results: Maximum LOD = 3.16, Mo...... Two-point parametric linkage results: Maximum LOD = 3.16, Model BP3, Dominant, theta = 0.15 More...	Suggestive linkage was found in this region. Suggestive linkage was found in this region.	Trend

Region related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
LRBA	LPS-responsive vesicle trafficking, beach and anchor containing	4q13	1(0/0/1)
NR3C2	nuclear receptor subfamily 3, group C, member 2	4q31	1(1/0/0)

View in gBrowse

Region: chr4:138500000..154600000 View in gBrowse