BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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KEGG Pathway Report

Basic Info

ID	hsa00260
Name	Glycine, serine and threonine metabolism
No. of Genes in BDgene	3
Source	Pathway by PBA

PBA Result

Pathway Name in Paper	Source	Reference	Data Set	Tool	Result Parameters	Result Link
Glycine, serine and threonine metabolism	PBA paper	Chen, L., 2009	WTCCC	Prioritizing Risk Pathways fusing SNPs and pathways (PRP)	risk score=0.67
Glycine, serine and threonine metabolism	PBA paper	Peng, G., 2010	WTCCC	hypergeometric test (Fisher's exact test), Sidak's method, Simes' method, Simes/FDR method	Fisher exact test P-value=0.00413244

Pathway related genes in BDgene (count: 3)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
MAOB	monoamine oxidase B	Xp11.4-p11.3	4(2/2/0)
MAOA	monoamine oxidase A	Xp11.4-p11.3	21(10/11/0)
DAO	D-amino-acid oxidase	12q24.11	5(1/4/0)