Overview of Genome-wide Linkage Studies in BDgene

Search by: Study Type = genome-wide linkage

Total result: 51

Reference	Study Design	Study Type	Ethnicity	Age Group	Sample Size	No. of Reported Regions
Del Zompo, M.,2010	affected sib pairs	Genome-wide linkage study	Caucasian	Adults	The sib-pair collection consisted of 88 nuclear families with a total of 381 individuals(210 affected individuals)	34
Kremeyer,B.,2010	pedigree	Genome-wide linkage study		Adults	Fifteen extended pedigrees comprised 90 cases of BPI, 22 cases of major depression, and 1 case each of schizophrenia and BPII	5
Lopez de Lara, C.,2010	family-based	Genome-wide linkage study	Caucasian	Adults	36 families (275 genotyped individuals, 132 affected)	5
McAuley, E. Z.,2009	pedigree	Genome-wide linkage study			35-pedigree cohort	9
Evans, L. M.,2008	pedigree	Genome-wide linkage study			28 BP families with 158 individuals	1
Fullerton, J. M.,2008	pedigree	Genome-wide linkage study			15 bipolar affective disorder pedigrees comprising 63 affected and 158 nonaffected individuals	31
Venken, T.,2008	pedigree	Genome-wide linkage study	Caucasian	Adults	176 individuals from the 10 families	13
Cassidy, F.,2007	pedigree	Genome-wide linkage study	Caucasian		60 independent broadly defined ASPs (32 narrow) and a maximum of 98 broadly defined sib pairs (all possible, 38 narrow).	22
Jones, I.,2007	pedigree	Genome-wide linkage study	Caucasian		36 pedigrees contributed 54 affected sibling pairs	23
Nwulia, E. A.,2007	pedigree	Genome-wide linkage study			74 pedigrees that had BD II exclusively with 146 all possible relative-pairs	11
Zandi, P. P.,2007	pedigree	Genome-wide linkage study			428 subjects in 98 BP families	10
Service, S.,2006	pedigree	Genome-wide linkage study			Pedigree CR201 with 168 members	24
Etain, B.,2006	pedigree	Genome-wide linkage study	Caucasian		87 sib-pairs from 70 nuclear families ascertained through an early-onset BPAD type I proband.	19
Marcheco-Teruel, B.,2006	pedigree	Genome-wide linkage study	Caucasian		a six generation pedigree with 28 affected members	29
Ewald, H.,2005	pedigree	Genome-wide linkage study	Caucasian		24 persons with bipolar disorder from 22 inbred families.	3
Maziade, M.,2005	pedigree	Genome-wide linkage study		Adults	21 multigenerational families of Eastern Quebec affected by SZ, BP or both(N=480 family members).	10
Schumacher, J.,2005	pedigree	Genome-wide linkage study	Caucasian		52 families (448 genotyped individuals) for genomewide scan;108 families (728 genotyped individuals) for fine-mapping linkage analysis	5
Fallin, M. D.,2004	pedigree	Genome-wide linkage study	Caucasian	Adults	41 pedigrees with a proband affected with bipolar I disorder (BPI) and at least one other member affected with BPI or bipolar II disorder (BPII)	9
Middleton, F. A.,2004	pedigree	Genome-wide linkage study			12 families	9
Pato, C. N.,2004	pedigree	Genome-wide linkage study			16 families with bipolar disorder containing 102 members	9
Ekholm, J. M.,2003	pedigree	Genome-wide linkage study	Caucasian		41 families with at least two affected siblings	9
Liu, J.,2003	pedigree	Genome-wide linkage study	Caucasian	Adults	373 individuals in 40 pedigrees	18
McInnis, M. G.,2003(b)	pedigree	Genome-wide linkage study			573 interviewed and genotyped subjects ascertained through 65 BPI probands.	15
Curtis, D.,2003	pedigree	Genome-wide linkage study	Caucasian		Seven pedigrees containing multiple cases of bipolar and unipolar affective disorder	19
Badenhop, R. F.,2002	pedigree	Genome-wide linkage study	Caucasian		13 pedigree cohort consisted of 231 individuals, including 69 affected members	11
Bailer, U.,2002	pedigree	Genome-wide linkage study	Caucasian	Adults	five schizophrenia families and three bipolar disorder families	17
Bennett, P.,2002	pedigree	Genome-wide linkage study	Caucasian		509 subjects from 151 nuclear families	19
Ekholm, J. M.,2002	pedigree	Genome-wide linkage study	Caucasian	Adults	a total of 154 affected individuals in 41 Finnish bipolar families	1
Ewald, H.,2002	pedigree	Genome-wide linkage study	Caucasian		Two families identified through bipolar probands	6
Ophoff, R. A.,2002	pedigree	Genome-wide linkage study			266 genotyped individuals (109 probands and 157 parents).	34
Badenhop, R. F., 2001	pedigree	Genome-wide linkage study	Caucasian		40 individuals, including six affecteds	5
Cichon, S.,2001(b)	pedigree	Genome-wide linkage study	Caucasian		75 families with 444 individuals	7
Maziade, M.,2001	pedigree	Genome-wide linkage study		Adults	480 individuals from 21 multigenerational pedigrees	3
Friddle, C.,2000	pedigree	Genome-wide linkage study	Caucasian		50 families containing 470 individuals, among whom there were 108 BPI phenotypes,75 BPII phenotypes, and 53 RUP phenotypes	3
Murphy, V. E.,2000	affected sib pairs	Genome-wide linkage study	Caucasian		48 families with bipolar disorder, comprising a total of 82 affected sib-pairs.	56
Palo, O. M.,2010	family-based	Genome-wide linkage study and candidate-gene association study	Caucasian		23 late settlement families, consisting of 147 individuals including 68 affected with broad mood disorder for the linkage scan;179 families that included the initial 23 late settlement families consisted of 723 individuals including 298 affected with broad mood disorder for further linkage and association analyses	7
Fullerton, J. M.,2010	pedigree and case-control	Genome-wide linkage study and genetic interaction study			65 Australian extended pedigrees containing 643 genotyped individuals (of whom 40% were diagnosed with affective disorder);WTCCC and GAIN datasets: 2933 bipolar disorder (and related disorder) cases and 2534 control subjects.	7
Badner, J. A.,2012	pedigree	Genome-wide linkage study			972 bipolar pedigrees including 2284 cases of BPI disorder, 498 individuals with bipolar II disorder (BPII) and 702 subjects with recurrent major depression	38
Goes, F. S.,2007	pedigree	Genome-wide linkage study			3,643 subjects in 708 families	38
Kerner, B.,2007	pedigree	Genome-wide linkage study			332 affected relative pairs in 138 families	5
Ross, J.,2008	pedigree	Genome-wide linkage study			644 bipolar families containing 1565 individuals	13
McInnis, M. G.,2003(a)	pedigree	Genome-wide linkage study			153 pedigrees	11
Willour, V. L.,2003	pedigree	Genome-wide linkage study			Fifty-six bipolar pedigrees with 354 genotyped subjects	3
Zandi, P. P.,2003	pedigree	Genome-wide linkage study			Fifty-six bipolar pedigrees with 354 genotyped subjects	2
Dick, D. M.,2002	pedigree	Genome-wide linkage study			540 subjects from 97 families	2
Garner, C.,2001	pedigree	Genome-wide linkage study			a Complex Pedigree with Severe Bipolar Disorder	30
Kelsoe, J. R.,2001	pedigree	Genome-wide linkage study			57 families including 345 subjects(169 with bipolar I disorder, 36 with bipolar II disorder, and 45 with recurrent major depression)	30
Foroud, T.,2000	pedigree	Genome-wide linkage study			97 families including 232 subjects diagnosed with bipolar I (BPI), 32 with schizo-affective, bipolar type (SABP), 72 with bipolar II (BPII), and 88 with unipolar recurrent depression (UPR).	4
Fanous, A. H.,2012	pedigree	Genome-wide Linkage Study			52 BD, 44 SZ, and 90 PSY total genotyped sibling pairs, respectively,from 47 families	13
Greenwood, T. A.,2012	pedigree	Genome-wide Linkage Study			229 individuals from 34 families	18
Gonzalez, S., 2014	family-based	Genome-wide linkage study	Caucasian		3757 participants included 963 individuals with BP phenotype (704 relative pairs) from 686 families, 393 ethnically matched healthy Latino individuals	3