Overview of Genome-wide Association Studies in BDgene

Search by: Study Type = GWAS

Total result: 41

Reference	Study Design	Study Type	Ethnicity	Age Group	Sample Size	No. of Reported SNPs/Genes
Hamshere, M. L.,2009	case-control	Genome-wide association study	Caucasian	Adults	1868 individuals with bipolar disorder and 2938 controls	10 / 8
Hattori, E.,2009	case-control	Genome-wide association study	Mongloid	Adults	107 cases with bipolar I disorder and 107 controls	89 / 31
Moskvina, V.,2009	case-control	Genome-wide association study			1868 bipolar disorder cases,479 UK schizophrenia cases and 2938 controls	0 / 52
Scott, L. J.,2009	case-control	Genome-wide association study	Caucasian	Adults	(i) 2,076 bipolar cases and 1,676 controls of European ancestry from the National Institute of Mental Health Human Genetics Initiative Repository, and the Prechter Repository and samples collected in London, Toronto, and Dundee.(ii)1,868 BP cases and an expanded reference set of 12,831 individuals from the Wellcome Trust Case Control Consortium (WTCCC).	23 / 0
Smith, E. N.,2009	case-control	Genome-wide association study			1346 BD cases (1001 EA subjects and 345 AA subjects) and 1703 control(1033 EA subjects and 670 AA subjects)	10 / 7
Ancin, I.,2011(b)	case-control	Genome-wide association study	Caucasian		784 healthy controls and 238 euthymic bipolar patients for case- control study,a subgroup consisted of 95 healthy controls and 122 BD patients for the sensory gating association analysis	3 / 1
Cichon, S.,2011	case-control	Genome-wide association study	Caucasian		682 patients with BD and 1300 controls	48 / 7
Curtis, D.,2011	case-case	Genome-wide association study	Caucasian		506 patients with bipolar 1 disorder, 523 patients with schizophrenia and 505 controls.	8 / 7
Lee, M. T.,2011	case-control	Genome-wide association study	Mongloid		1000 bipolar I patients and 1000 controls	8 / 5
Yosifova, A.,2011	case-control	Genome-wide association study	Caucasian		188 bipolar disorder patients and 376 control subjects	14 / 11
Liu, X.,2010	case-control	Genome-wide association study		Adolescents	Thirty-nine patients with BD and 29 healthy controls	1 / 1
Djurovic, S.,2010	case-control	Genome-wide association study	Caucasian		Norwegian sample including patienst with bipolar disorder (n=194), healthy controls (n=336) and patients with schizophrenia (n=230)	49 / 17
The Wellcome Trust Case Control Consortium, 2007	case-control	Genome-wide association study	Caucasian	adolescents and adults	1,868 cases, 2,938 controls	14 / 0
Baum, A. E., 2008 (a)	case-control	Genome-wide association study	Caucasian		461 BD and 563 controls	38 / 0
Ferreira, M. A.,2008	case-control	Genome-wide association study			4,387 cases and 6,209 controls	6 / 0
Sklar, P., 2008	case-control	Genome-wide association study	Caucasian	adults	1461 patients with bipolar (BP) 1 disorder, 2008 controls	20 / 8
Jiang, Y.,2011	case-control	Genome-wide association study			1,998 BD cases and 3,004 controls	61 / 0
Ross, K. A.,2011	case-control	Genome-wide association study			2000 cases and 1500 controls	5 / 4
Huang, J.,2010	case-control	Genome-wide association study			schizophrenia (CATIE, genotyped:N=741), bipolar disorder (STEP-BD, genotyped:N=1,575), and major depressive disorder (STAR*D, genotyped: N=1,938) as well as from psychiatrically screened control subjects (NIMH-Genetics Repository:N=1,204)	25 / 22
Bergen, S. E.,2012	case-control	Genome-wide association study	Caucasian	Adults	1507 SCZ cases, 836 BD cases and 2093 controls	27 / 17
Green, E. K.,2012	case-control	Genome-wide association study	Caucasian		1218 bipolar disorder (BD) cases and 2913 controls	27 / 17
Nissen, S.,2012	case-control and family based	Genome-wide association study	Caucasians		598 individuals and 352 cases from 169 families	0 / 0
Lee, H. J., 2013	case-control	Genome-wide association study			1001 BD cases and 1033 controls for the initial sample, 1190 BDcases, 401 controls for the second sample	23 / 3
Steinberg, S.,2012	case-control	Genome-wide association study			Here we consider a mixed schizophrenia and bipolar disorder (psychosis) phenotype (addition of 7469 bipolar disorder cases, 1535 schizophrenia cases, 333 other psychosis cases, 808 unaffected family members and 46 160 controls)	9 / 4
Cross-Disorder Group of the Psychiatric Genomics Consortium,2013	case-control	Genome-wide association study	Caucasian		The final dataset consisted of 33 332 cases and 27 888 controls(including pseudocontrols formed from nontransmitted alleles) distributed among the five disorder groups: autism spectrum disorders (4788 trio cases, 4788 trio pseudocontrols, 161 cases, 526 controls), attention defi cit-hyperactivity disorder (1947 trio cases, 1947 trio pseudocontrols, 840 cases, 688 controls), bipolar disorder (6990 cases, 4820 controls), major depressive disorder (9227 cases, 7383 controls), and schizophrenia (9379 cases, 7736 controls).	10 / 9
Major Depressive Disorder Working Group of the Psychiatric, G. C., 2013	case-control	mega-analysis of Genome-wide association study	Caucasian		9,238 MDD cases plus 8,039 controls and 6,998 BIP cases plus 7,775 controls	15 / 0
Andreassen OA, 2013	case-control	GWAS			n= 9379 cases and n =7736 control samples in schizophrenia, and n= 6990 cases and n =4820 controls in bipolar disorder	106 / 0
Ruderfer, D. M., 2013	case-control	Genome-wide association study			19 779 cases (9369 SCZ plus 10 410 BP) versus 19423 controls for combined GWAS, 7129 SCZ cases versus 9252 BP cases for a direct comparison GWAS	6 / 5
Lencz, T., 2013	case-control	Genome-wide association study and Meta-analysis			904 schizophrenia cases and 1,640 controls for discovery GWAS	1 / 1
Georgi, B., 2014	family-based & pedigree	Genome-wide association study, Linkage study, Mutational study	Caucasian	adults	497 individuals from a large pedigree were used for linkage analysis using microsatellite data. 388 out of them were used for genotyping using illumina Omni SNP array. 50 out of them were for whole genome sequencing, comprising 18 parent-child trios.	73 / 63
Kuo, P. H., 2014	case-control	Genome-wide association study	Mongloid	adults	200 BPD-1 patients and 200 controls	22 / 8
Muhleisen, T. W., 2014	case-control	Genome-wide association study	Caucasian		9747 (2266 from MooDS, 7481 from PGC) patients and 14278 (5028 from MooDS, 9250 from PGC) controls	18 / 6
Xu, W., 2014	case-control and family-based	Genome-wide association study	Caucasian	adults	From Toronto constituting: 431 cases and 440 controls; from UK: 538 cases and 513 controls.	319 / 119
Saito T., 2014	case-control	Genome-wide association study	Mongloid	adults	1032 SCZ, 1012 BD(BD typeI=621, BD typeII=380, schizoaffective disorder [SA]=7, BD type information not available=4) and 993 controls.	9 / 9
Winham S.J., 2014	case-control	Genome-wide association study	Caucasian	adults	1001 bipolar cases and 1034 controls	13 / 11
Jamain, S., 2014	case-control	Genome-wide association study	Caucasian		GWAS: 211 patients of French and 1719 controls	38 / 22
Strauss, K. A., 2014	family-based	Genome-wide association study	Caucasian	adult	26 Amish subjects from 4 families	9 / 10
Chen, X., 2015	case-control	Genome-wide association study	Han Chinese	adults	119 SCZ, 253 BPD (type-I), 177 MDD, 1000 controls	32 / 32
Cho, C. H., 2015	case-control	Genome-wide association study			2,191 cases, 1,434 controls	1 / 2
Forstner, A. J., 2015	case-control	Genome-wide association study			9,747 patients, 14,278 controls	9 / 0
Liu, X., 2016	case-control	Genome-wide association study			184 bipolar subjects with eating disorder comorbidity, 1370 controls and 2006 subjects with bipolar disorder only	12 / 0