BDgene

Overview of Genome-wide Association Studies in BDgene

Search by: Study Type = GWAS

Total result: 41

Reference Study Design Study Type Ethnicity Age Group Sample Size No. of Reported SNPs/Genes
Hamshere, M. L.,2009 case-control Genome-wide association study Caucasian Adults 1868 individuals with bipolar disorder and 2938 controls 10 / 8
Hattori, E.,2009 case-control Genome-wide association study Mongloid Adults 107 cases with bipolar I disorder and 107 controls 89 / 31
Moskvina, V.,2009 case-control Genome-wide association study 1868 bipolar disorder cases,479 UK schizophrenia cases and 2938 controls 0 / 52
Scott, L. J.,2009 case-control Genome-wide association study Caucasian Adults (i) 2,076 bipolar cases and 1,676 controls of European ancestry from the National Institute of Mental Health Human Genetics Initiative Repository, and the Prechter Repository and samples collected in London, Toronto, and Dundee.(ii)1,868 BP cases and an expanded reference set of 12,831 individuals from the Wellcome Trust Case Control Consortium (WTCCC). 23 / 0
Smith, E. N.,2009 case-control Genome-wide association study 1346 BD cases (1001 EA subjects and 345 AA subjects) and 1703 control(1033 EA subjects and 670 AA subjects) 10 / 7
Ancin, I.,2011(b) case-control Genome-wide association study Caucasian 784 healthy controls and 238 euthymic bipolar patients for case- control study,a subgroup consisted of 95 healthy controls and 122 BD patients for the sensory gating association analysis 3 / 1
Cichon, S.,2011 case-control Genome-wide association study Caucasian 682 patients with BD and 1300 controls 48 / 7
Curtis, D.,2011 case-case Genome-wide association study Caucasian 506 patients with bipolar 1 disorder, 523 patients with schizophrenia and 505 controls. 8 / 7
Lee, M. T.,2011 case-control Genome-wide association study Mongloid 1000 bipolar I patients and 1000 controls 8 / 5
Yosifova, A.,2011 case-control Genome-wide association study Caucasian 188 bipolar disorder patients and 376 control subjects 14 / 11
Liu, X.,2010 case-control Genome-wide association study Adolescents Thirty-nine patients with BD and 29 healthy controls 1 / 1
Djurovic, S.,2010 case-control Genome-wide association study Caucasian Norwegian sample including patienst with bipolar disorder (n=194), healthy controls (n=336) and patients with schizophrenia (n=230) 49 / 17
The Wellcome Trust Case Control Consortium, 2007 case-control Genome-wide association study Caucasian adolescents and adults 1,868 cases, 2,938 controls 14 / 0
Baum, A. E., 2008 (a) case-control Genome-wide association study Caucasian 461 BD and 563 controls 38 / 0
Ferreira, M. A.,2008 case-control Genome-wide association study 4,387 cases and 6,209 controls 6 / 0
Sklar, P., 2008 case-control Genome-wide association study Caucasian adults 1461 patients with bipolar (BP) 1 disorder, 2008 controls 20 / 8
Jiang, Y.,2011 case-control Genome-wide association study 1,998 BD cases and 3,004 controls 61 / 0
Ross, K. A.,2011 case-control Genome-wide association study 2000 cases and 1500 controls 5 / 4
Huang, J.,2010 case-control Genome-wide association study schizophrenia (CATIE, genotyped:N=741), bipolar disorder (STEP-BD, genotyped:N=1,575), and major depressive disorder (STAR*D, genotyped: N=1,938) as well as from psychiatrically screened control subjects (NIMH-Genetics Repository:N=1,204) 25 / 22
Bergen, S. E.,2012 case-control Genome-wide association study Caucasian Adults 1507 SCZ cases, 836 BD cases and 2093 controls 27 / 17
Green, E. K.,2012 case-control Genome-wide association study Caucasian 1218 bipolar disorder (BD) cases and 2913 controls 27 / 17
Nissen, S.,2012 case-control and family based Genome-wide association study Caucasians 598 individuals and 352 cases from 169 families 0 / 0
Lee, H. J., 2013 case-control Genome-wide association study 1001 BD cases and 1033 controls for the initial sample, 1190 BDcases, 401 controls for the second sample 23 / 3
Steinberg, S.,2012 case-control Genome-wide association study Here we consider a mixed schizophrenia and bipolar disorder (psychosis) phenotype (addition of 7469 bipolar disorder cases, 1535 schizophrenia cases, 333 other psychosis cases, 808 unaffected family members and 46 160 controls) 9 / 4
Cross-Disorder Group of the Psychiatric Genomics Consortium,2013 case-control Genome-wide association study Caucasian The final dataset consisted of 33 332 cases and 27 888 controls(including pseudocontrols formed from nontransmitted alleles) distributed among the five disorder groups: autism spectrum disorders (4788 trio cases, 4788 trio pseudocontrols, 161 cases, 526 controls), attention defi cit-hyperactivity disorder (1947 trio cases, 1947 trio pseudocontrols, 840 cases, 688 controls), bipolar disorder (6990 cases, 4820 controls), major depressive disorder (9227 cases, 7383 controls), and schizophrenia (9379 cases, 7736 controls). 10 / 9
Major Depressive Disorder Working Group of the Psychiatric, G. C., 2013 case-control mega-analysis of Genome-wide association study Caucasian 9,238 MDD cases plus 8,039 controls and 6,998 BIP cases plus 7,775 controls 15 / 0
Andreassen OA, 2013 case-control GWAS n= 9379 cases and n =7736 control samples in schizophrenia, and n= 6990 cases and n =4820 controls in bipolar disorder 106 / 0
Ruderfer, D. M., 2013 case-control Genome-wide association study 19 779 cases (9369 SCZ plus 10 410 BP) versus 19423 controls for combined GWAS, 7129 SCZ cases versus 9252 BP cases for a direct comparison GWAS 6 / 5
Lencz, T., 2013 case-control Genome-wide association study and Meta-analysis 904 schizophrenia cases and 1,640 controls for discovery GWAS 1 / 1
Georgi, B., 2014 family-based & pedigree Genome-wide association study, Linkage study, Mutational study Caucasian adults 497 individuals from a large pedigree were used for linkage analysis using microsatellite data. 388 out of them were used for genotyping using illumina Omni SNP array. 50 out of them were for whole genome sequencing, comprising 18 parent-child trios. 73 / 63
Kuo, P. H., 2014 case-control Genome-wide association study Mongloid adults 200 BPD-1 patients and 200 controls 22 / 8
Muhleisen, T. W., 2014 case-control Genome-wide association study Caucasian 9747 (2266 from MooDS, 7481 from PGC) patients and 14278 (5028 from MooDS, 9250 from PGC) controls 18 / 6
Xu, W., 2014 case-control and family-based Genome-wide association study Caucasian adults From Toronto constituting: 431 cases and 440 controls; from UK: 538 cases and 513 controls. 319 / 119
Saito T., 2014 case-control Genome-wide association study Mongloid adults 1032 SCZ, 1012 BD(BD typeI=621, BD typeII=380, schizoaffective disorder [SA]=7, BD type information not available=4) and 993 controls. 9 / 9
Winham S.J., 2014 case-control Genome-wide association study Caucasian adults 1001 bipolar cases and 1034 controls 13 / 11
Jamain, S., 2014 case-control Genome-wide association study Caucasian GWAS: 211 patients of French and 1719 controls 38 / 22
Strauss, K. A., 2014 family-based Genome-wide association study Caucasian adult 26 Amish subjects from 4 families 9 / 10
Chen, X., 2015 case-control Genome-wide association study Han Chinese adults 119 SCZ, 253 BPD (type-I), 177 MDD, 1000 controls 32 / 32
Cho, C. H., 2015 case-control Genome-wide association study 2,191 cases, 1,434 controls 1 / 2
Forstner, A. J., 2015 case-control Genome-wide association study 9,747 patients, 14,278 controls 9 / 0
Liu, X., 2016 case-control Genome-wide association study 184 bipolar subjects with eating disorder comorbidity, 1370 controls and 2006 subjects with bipolar disorder only 12 / 0