Gene Report

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Basic Info

Approved Symbol	SLC2A9
Symbol Alias	Glut9, GLUTX, URATv1
Approved Name	solute carrier family 2 (facilitated glucose transporter), member 9
Name Alias	urate voltage-driven efflux transporter 1
Location	4p16.1
Position	chr4:9771153-10054936, -1
External Links	HGNC: 13446 Entrez Gene: 56606 Ensembl: ENSG00000109667 UCSC: uc003gmc.3
No. of Studies	1 (Positive: 0; Negative: 0; trend: 1)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Le Hellard, S., 2007		We examined the 48 SNPs in the significant shared region and thirty-three of the SNPs are in SLC2A9. Description of a 200-kb region of increased allele sharing prioritizes this region, which contains two functional candidate genes for BPAD, SLC2A9, and WDR1, for subsequent studies.	Trend	Comment on Study

Gene functional annotation

Gene related GO terms (count: 12)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0005887	integral component of plasma membrane	cellular component	IEA	158
GO:0016021	integral component of membrane	cellular component	NAS[10860667]	219
GO:0005886	plasma membrane	cellular component	TAS	360

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0055085	transmembrane transport	biological process	TAS	77
GO:0005355	glucose transmembrane transporter activity	molecular function	IEA	1
GO:0015758	glucose transport	biological process	NAS[10860667]	7
GO:0015992	proton transport	biological process	NAS[10860667]	4
GO:0016324	apical plasma membrane	cellular component	IEA	24
GO:0005635	nuclear envelope	cellular component	IEA	10
GO:0046415	urate metabolic process	biological process	IMP[18834626]	2
GO:0005351	sugar:proton symporter activity	molecular function	NAS[10860667]	1
GO:0016323	basolateral plasma membrane	cellular component	IEA	21

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 4)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
Chr 4	chr4:0-190214555	3 (0/3/0)
4p16.1	chr4:6000000-11300000	2 (0/2/0)
4p16	chr4:0-11300000	2 (0/1/1)
4p	chr4:0-50000000	1 (0/1/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

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Region: chr4:9771153..10054936 View in gBrowse