Gene Report

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Basic Info

Approved Symbol	MAB21L1
Symbol Alias	CAGR1
Approved Name	mab-21-like 1 (C. elegans)
Previous Name	mab-21 (C. elegans)-like 1
Location	13q13.3
Position	chr13:35474182-35477209, -1
External Links	HGNC: 6757 Entrez Gene: 4081 Ensembl: ENSG00000180660 UCSC: uc032aca.1
No. of Studies	1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Meira-Lima, I. V.,2001	Other variant: MAB21L1_CAG/CTG repeat	Our data do not support the hypothesis that variation at the polymorphic CAG/CTG repeat loci MAB21L influence susceptibility to BPAD in our sample.	Negative	Comment on Study

Gene functional annotation

Gene related GO terms (count: 5)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0005634	nucleus	cellular component	IEA	283

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0009653	anatomical structure morphogenesis	biological process	TAS[8733127]	6
GO:0005515	protein binding	molecular function	IPI[25416956]	563
GO:0043010	camera-type eye development	biological process	IEA	3
GO:0008284	positive regulation of cell proliferation	biological process	IEA	44

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 1)

Variant Name	Variant Type	Location in Gene	No. of Studies (Positive/Negative/Trend)
MAB21L1_CAG/CTG repeat	microsatellite		1 (0/1/0)

Gene related regions (count: 6)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
13p11.1-13q13	chr13:16500000-39500000	1 (0/0/1)
13q13	chr13:31600000-39500000	1 (0/0/1)
13q12-14	chr13:18900000-54700000	1 (0/1/0)
13q13-q14	chr13:31600000-54700000	1 (1/0/0)
Chr 13	chr13:0-114364328	1 (0/0/1)
13q13.3-q14.11	chr13:34900000-44600000	1 (0/1/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

View in gBrowse

Region: chr13:35474182..35477209 View in gBrowse