Gene Report

ADD to My Gene Set

Basic Info

Approved Symbol	GUCY1B2
Symbol Alias	GC-SB2
Approved Name	guanylate cyclase 1, soluble, beta 2 (pseudogene)
Previous Name	guanylate cyclase 1, soluble, beta 2
Location	13q14.3
Position	chr13:50994511-51080862, -1
External Links	HGNC: 4686 Entrez Gene: 2974 Ensembl: ENSG00000123201 UCSC: uc010tgo.2
No. of Studies	1 (Positive: 0; Negative: 0; trend: 1)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Djurovic, S.,2010	SNP: rs11617400, rs7317089	Suggestive association of this gene was found(P-values ranging from 5.39E-07 to 9.95E-05).	Trend	Comment on Study

Gene functional annotation

Gene related GO terms (count: 0)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 7)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs11617400	chr13:51003439 - 51003439(1)	downstream_gene_variant; intron_variant; non_coding_transcript_variant	1(0/0/1)
rs7317089	chr13:51006384 - 51006384(1)	downstream_gene_variant; intron_variant; non_coding_transcript_variant	1(0/0/1)

rs_ID	Location	Functional Annotation
rs7332491	chr13:51005549 - 51005549(1)	downstream_gene_variant; intron_variant; non_coding_transcript_variant
rs7339210	chr13:51006401 - 51006401(1)	downstream_gene_variant; intron_variant; non_coding_transcript_variant
rs3790020	chr13:51002933 - 51002933(1)	downstream_gene_variant; intron_variant; non_coding_transcript_variant
rs11618422	chr13:51003334 - 51003334(1)	downstream_gene_variant; intron_variant; non_coding_transcript_variant
rs3790021	chr13:51002748 - 51002748(1)	downstream_gene_variant; intron_variant; non_coding_transcript_variant

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 4)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
13q12-14	chr13:18900000-54700000	1 (0/1/0)
13q14	chr13:39500000-54700000	3 (0/1/2)
13q13-q14	chr13:31600000-54700000	1 (1/0/0)
Chr 13	chr13:0-114364328	1 (0/0/1)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

View in gBrowse

Region: chr13:50994511..51080862 View in gBrowse