Gene Report

Basic Info
Approved Symbol CDH13
Symbol Alias CDHH
Approved Name cadherin 13
Name Alias T-cadherin, "H-cadherin (heart)"
Location 16q23.3
Position chr16:82626803-83800640, 1
External Links HGNC: 1753
Entrez Gene: 1012
Ensembl: ENSG00000140945
UCSC: uc010vns.2
No. of Studies 3 (Positive: 2; Negative: 1; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 3)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Xu, W., 2014 SNP: rs11640984, rs11644289, rs11649622, rs12448273, rs4782731, rs6565063, rs7186123, rs7201194 The SNP within or near this gene did not achieve genome-wide significance. Negative Comment on Study
Johnson, C.,2009 Monte-Carlo Simulation P-value = 0.0017. One of Genes That Harbor Overlapping Clusters of 4 Nominally Positive SNPs Whose Allele Frequencies Distinguish Individuals With Bipolar Disorder From Controls With P<0.05 Nominal Significance From at Least Three of the Four Samples in This Analysis Positive Comment on Study
Cho, C. H., 2015 CDH13 is located in 16q24.2 and encodes a member of the cadherin superfamily. The encoded protein acts as a negative regulator of axon growth during neural differentiation. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 39)

GO terms by PBA (count: 3)

GO terms by database search (count: 36)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 1)

Related other genetic factors
Gene related SNPs (count: 29)

Literature-origin SNPs (count: 8)

LD-proxies (count: 21)

Gene related CNVs (count: 1)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr16:82626803..83800640 View in gBrowse
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